Diffractometer, Erythrocyte, Blood
Sunday, September 03, 2006
A Blood Erythrocyte Diffractometer has been designed and developed for measuring permeability of a membrane and the Erythrocyte change of a membrane. The Diffractometer consists of optical channels and hydrodynamic channels.
A blood microsample drips in a mixer filled with a solution. The resulting Erythrocyte suspension trickles down a pipe into a drain vessel. A flat glass cell is fitted into the pipe. A laser light beam travels perpendicular through the glass cell. The laser light beam is scattered by the Erythrocyte flowing through the glass cell. The scattered light falls on a frosted screen that is focused by a lens to a focal plane. A decrease in membrane permeability can indicate acute poison level from barbiturates, narcotics, alcohol and others. This method allows for the rapid determination of the level of poison in blood.
Source: "Laser erythrocyte diffractometer", by I. Z. Nemtsev, Optical Engineering Bulletin, May 1995.
Reference:
1) "Laser erythrocyte diffractometer", by I. Z. Nemtsev, Optical Engineering Bulletin, May 1995.
2) "Diffractometric control in erythrocyte damage low-energy treatment", by I. Z. Nemtsev, Biochemical Diagnostic Instrumentation, R. Bonner, G. Cohn, T. Laue, A. Priezzhev, Editors, Proc. SPIE, Vol. 136, pp. 119-126, 1994.
3) "15-years experience of low-energy lasers application for patients treatment in emergency care clinics", by I. Z. Nemtsev, V. P. Lapshin, Cell and Biotissue Optics, V. Tuchin, Editor, Proc. SPIE. Vol. 2100, pp. 284-291, 1994.
4) "New optical technique for measuring erythrocyte deformability with ectacytometer", by W. Grower, N. Mohandas, and M. Bessis, Clin. Chem., Vol. 26, pp. 1435-1442, 1980.
5) I. Z. Nemtsev, Head of the Laser Research Group; N. V. Sklifosovsky Research Institute for Medicine; 4-6, korp. 4, Kuusinena Str., App. 545; Moscow, 123308 Russia;
Industrial Products
posted by JD52 @ 12:39 AM,
